Science is often a piecemeal process, with each small, new discovery adding another insight into the mysterious mechanisms behind how our bodies work. A new finding from the University of Virginia School of Medicine adds another piece to the puzzle of how cells in our body degrade with age. The potentially revolutionary breakthrough reveals how our cells can wrinkle with age, resulting in genes not being expressed properly. And the solution could be a novel cellular anti-wrinkle cream, delivered by custom-built viruses.
The research initially found that inside an individual cell’s nucleus, the location of our DNA is fundamentally important for it to function correctly. Genes that sit up against the nuclear membrane, the wall that encases the nucleus, tend to remain switched off. However, as we age these membranes tend to become irregular in shape, or wrinkly, and genes that should remain switched off may become over-expressed.
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